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  • 此類抗生素對EnterococcusListeria無效
  • this generation of cephalosporin is active against G(+) and G(-)
  • have greater resistance to beta-lactamase than 3rd. generation one.
  • can pass BBB, thus can treat meningitis
  • against pseudomonas

例子編輯

  • cefepime
    • they also effective toward of Neisseria and Haemophilus
    • can pass BBB, thus can treat meningitis
    • against pseudomonas
    • cleared by kidney (thus dose-adjustment is needed when renal problem ). and pharmacokinetics is similar to 3rd. generation ceftazidime
    • against most penicillin-resistant streptococcienterobacter

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