重點[]
本類藥物的藥物動力學和BA未必有關係
機轉[]
pure antagonist[]
.
partial agonist(所謂有ISA的beta-阻斷劑)[]
.
inverse agonist[]
治療學[]
- basic t10.2
- 腎臟排泄
- 肝臟代謝
- 心跳過快: atenolol
- 高血壓
- 一般人:propranolol、
- Pregnancy-induced hypertension
- first-semester不能用
- second and third semester可以用metoprolol、atenolol和labetalol
- 哺乳婦可以用比較少通過乳汁的metoprolol、propranolol和labetalol
- 缺血性心臟病:metoprolol(3)、propranolol(2)和timolol(1)
- CHF:metoprolol、bisoprolol和carvedilol
- open-angle glaucoma: timolol、betaxolol、carteolol、levobunolol和metipranolol
- hyperthyroidism:propranolol
- migrain:propranolol
- diminish protal vein pressure in patient with cirrhosis: propranolol和nadolol
- 出血過的用:nadolol+isosorbide mononitrate