包含:
因為不耐酶，所以和beta-lactamase inhibitor配伍
combination therapy[]
- penicillin-beta-lactamase inhibitor combinations
- Zosyn=tazobactam+piperacillin
- Unasyn=sulbactam+ampicillin
- augmentin=clavulanate+amoxicillin
- Timentin=clavulanate+ticarcillin
- 長用在免疫低下的病人或是好氧菌和厭氧菌混合感染 Ex. intra-abdominal infection
- spectrum depends on antibiotics component
- dose are the same as those used for the single agents except that the recommended dosage of piperacillin in the piperacillin-tazobactam combination is 3 g every 6 h.
- adjustment for renal insufficiency are decide according to penicillin component.